AN IMPORTANT ARTICLE FROM OUR EPAG, JEANATTE ANDERSEN!
Recently, our ERN ReCONNET ePAG representative for Systemic Lupus Erythematous (SLE), Jeanette Andersen, has co-authored an important article on children born to mothers with autoimmune rheumatic diseases published in a special edition on pregnancy of The Lancet Rheumatology, the world-leading public health journal.
This scientific article shed a light on how maternal autoimmune rheumatic diseases can influence the outcomes of children through several life stages. In particular, the authors underlined that during pregnancy, maternal inflammation and autoantibodies can hinder fetal development and lead to growth restriction, preterm birth, and low birth weight; prematurity, especially at extreme gestational ages, can in turn impair future child health. Investigations on how treatment with compatible immunomodulatory drugs and preventive medications aims to keep maternal disease under control and minimise the risk of adverse pregnancy outcomes from one side, however, concerns have been raised about their effects on neonatal conditions (ie, the risk of serious infections, inadequate responses to vaccinations, and organ toxicity) as well as long-term outcomes (metabolic and cardiovascular problems and neurodevelopmental disorders). Among the unmet needs of parents with autoimmune rheumatic diseases, there is the estimation of risk for the children to develop autoimmune disorders and the need for reassurance about parenting capacity while living with a chronic condition.
This scientific article shed a light on how maternal autoimmune rheumatic diseases can influence the outcomes of children through several life stages. In particular, the authors underlined that during pregnancy, maternal inflammation and autoantibodies can hinder fetal development and lead to growth restriction, preterm birth, and low birth weight; prematurity, especially at extreme gestational ages, can in turn impair future child health. Investigations on how treatment with compatible immunomodulatory drugs and preventive medications aims to keep maternal disease under control and minimise the risk of adverse pregnancy outcomes from one side, however, concerns have been raised about their effects on neonatal conditions (ie, the risk of serious infections, inadequate responses to vaccinations, and organ toxicity) as well as long-term outcomes (metabolic and cardiovascular problems and neurodevelopmental disorders). Among the unmet needs of parents with autoimmune rheumatic diseases, there is the estimation of risk for the children to develop autoimmune disorders and the need for reassurance about parenting capacity while living with a chronic condition.
At ERN ReCONNET, Jeanette is highly involved in several Network initiatives, she is one of our Steering Committee Member, an ePAG representative at our Research and Quality of Life Working Group led by Dr. Rosaria Talarico and ePAG Ilaria Galetti, and an ePGA representative for SLE together with Alain Cornet in the SLE Disease Group led by Prof. Laurent Arnaud and Prof. Maarten Limper.
Moreover, with a background education in German and Philosophy from the University of Copenhagen, she is the Chair of Lupus Europe, a EUPATI trained patient expert on medicines Research & Development and the leader of the Lupus Europe´s Patient Advisory Network (PAN); she is also a leader in the Danish Lupus group underneath Gigtforeningen (the Danish Rheumatism Association).
Moreover, with a background education in German and Philosophy from the University of Copenhagen, she is the Chair of Lupus Europe, a EUPATI trained patient expert on medicines Research & Development and the leader of the Lupus Europe´s Patient Advisory Network (PAN); she is also a leader in the Danish Lupus group underneath Gigtforeningen (the Danish Rheumatism Association).
This important article saw as authors also other ERN ReCONNET experts as Prof. Avcin and Prof. Tincani.
ERN RECONNET IS PROUD OF THIS RELEVANT ACHIEVEMENT AND
AS NETWORK WE CONGRATULATE TO JEANETTE, PROF. AVCIN, AND PROF. TINCANI FOR THIS VERY IMPORTANT ARTICLE,
WE ARE PROUD OF YOU!
More info on SLE can be found here.
The dedicated ERN ReCONNET YouTube Playlist on SLE webinars developed by our Network can be seen here – all webinars are freely available.
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