Webinar “Sex hormones and COVID-19: how is the game?”
1st June 2020 at 2:00 PM (CET) → Register here
Already from the earliest reports regarding the lethality risk after the COVID-19 infection, it is confirmed a significant increase of high morbidity and mortality in men compared to women.
Interestingly, average serum concentrations of SARS-CoV-2 IgG antibodies have been found (like after vaccinations) to be higher in women than in men in severe COVID-19 status.
In addition, the production of IgG seems to be stronger in female patients in the early phase of the SARS-CoV-2 infection.
Such important biological observation, should be considered expression of the crucial role played by the female hormone estrogens, and their receptors (ERs) signaling, in both innate and in particular adaptive (production of antibodies) immune responses.
Therefore, after COVID-19 infection the majority of female patients react immunologically better and may neutralize earlier the virus blocking the progression of the disease.
The Webinar will present the results of several detailed clinical studies and comparisons with the roles of estrogens in autoimmunity and after vaccinations.
Maurizio Cutolo is full professor of Rheumatology at University of Genoa. Director Research Laboratories and Academic Division of Rheumatology – Director Postgraduate School of Rheumatology – Deputy Chair of Department of Internal Medicine – University of Genova – IRCCS San Martino Polyclinic. Chairman Board Classrooms of the EULAR School of Rheumatology (ESoR) and Deputy-Chair of the European Rare Connective Tissue Disease Network ERN ReCONNET.
Cutolo is former President of the European League Against Rheumatism (EULAR) and Former Chairman of the International League of Associations for Rheumatology (ILAR). Former VPresident of the International Society for NeuroimmunoModulation (ISNIM) and VPresident of the Italian Society for Rheumatology. Honorary member of Russian, Hungarian Society of Rheumatology and EULAR. Doctor Honoris Causa of the University of Bucharest.
Basic/clinical research include, basic mechanisms of DMARDs in rheumatoid arthritis, systemic sclerosis, nailfold videocapillaroscopy in rheumatic diseases, neuroendocrine immunology, endocrine system of vitamin D, glucocorticoids and chronotherapy of rheumatoid arthritis.
The webinar recording is available here