B1MG project draws to a close
The Beyond 1 Million Genomes project (B1MG) has been a €4M three-year Coordination and Support Action to support the design and testing phase of the European 1+Million Genomes (1+MG) initiative. This initiative facilitates signatory countries to realise a practice of personalised medicine and health, based upon a shared ‘framework’ and the infrastructure to safely access and integrate high quality genomic data and other health data across borders.
During the project, experts across 25 countries produced many specific recommendations, guidelines and best practices that can be used to realise the 1+MG vision encompassing data governance, ethical, legal and social issues (ELSI), data models and quality, sequencing guidelines, technical infrastructure, implementation of genomics into healthcare, use cases and national resources. Consensus was reached at a European level by the 1+MG national experts for each area.
The European Genomic Data Infrastructure (GDI) project has already started to set up the infrastructure, building on B1MG recommendations, guidelines and best practices. This infrastructure will be available to be re-used for the management, access and analysis of human genomic and phenotypic information by European initiatives, research infrastructures, as well as EU and nationally funded projects. Ideally, they will be able to configure the components to fulfil their specific governance, operational and legal requirements, maximising the European Commission and national investments.
Here is a list of relevant information and documents to learn more about B1MG and GDI:
- The GDI Stakeholder Forum, which follows on from the B1MG Stakeholder Forums that support the 1+MG initiative, will take place on 23 November 2023 to share project information, updates and outcomes. This Stakeholder Forum will focus on informing industry stakeholders about the gaps and challenges faced by GDI and brainstorming potential solutions.
- B1MG recommendation on citizen engagement and public trust in genomic data sharing
- Roadmap and guidance tool for countries
- Report on legal set-up including Data Protection Impact Assessment
- Report on data access and governance framework
- Knowledge, attitudes and decision regret: a longitudinal survey study of participants offered genome sequencing in the 100,000 Genomes Project